6/07/25, Sunday, the following article in The New York Times,
formed the basis for Mr. [
195]'s request for a rdg.
describing how to make synthetic morphine:
METZ EXPLAINS REWARD FOR MORPHINE FORMULA
CHEMIST THINKS THAT MAKING THE DRUG SYNTHETICALLY WOULD END
POPPY GROWING AND OPIUM EVILS AND PREVENT WORLD STRIFE -
$100,000 PRIZE FOR SCIENTISTS By Silas Bent.
Herman A. Metz would fight fire with fire. He has offered
a $100,000 reward to the discoverer of a commercial formula
for synthetic morphine in the hope that opium, from which
morphine is derived, will thus be removed from the field
of international friction.
The line of reasoning that prompted this offer is easy to
follow. Poppies, from which opium is distilled, are grown
chiefly in India. The British Government maintains an opium
monopoly through which the drug is sold to unofficial
distributers. To maintain an open opium market England on
occasion has made war, and it was this interest that caused
her to block the International Opium Conference at Geneva.
But if morphine could be made in the laboratory more cheaply
than it can be reduced from the poppy pod poppy-growing
would no longer be profitable, the British opium monopoly
would disappear and a contentious issue of international
politics would be written off the books. This is Mr. Metz's
reasoning.
Several questions arise from this plan: What would be done
with the formula for morphine? What would be the effect on
the opium, morphine and heroin habits? Would moonshine
morphine, contraband heroin and bootleggers in drugs spring
up?
Mr. Metz, who was formerly City Controller, is a chemist and
inventor of some note. When I put these questions to him he
explained at once that his plan looked first to the
eliminating of opium from international politics rather than
to the checking of the drug habit.
ECONOMICS INVOLVED
"This is primarily an economic problem," he said, "and my
thought was to meet it economically. The suggestion really
came from a speech by Dr. Carlton Simon, who as a special
deputy police commissioner, is charged with suppressing the
drug traffic in New York. He said that the discovery of a
method of making morphine would be the best way of attacking
the drug habit. If the immense agricultural and commercial
interests which now cluster around the cultivation of the
poppy could be wiped out, Great Britain would cease to stand
in the way of international control of the traffic in
morphine and opium. It is not generally understood that
Great Britain could not suppress opium-growing in India
without provoking a revolution.
"We have an analogy in the case of indigo. When a synthetic
formula was found in 1902 for a dye exactly like indigo,
the cultivation of indigo ceased, for it was no longer
profitable.
"The first condition I made in regard to the $100,000 reward
is that the discoverer must relinquish all rights to it and
turn it over to the United States Government. The
Government would permit manufacture of morphine for medicinal
purposes under licenses, and supervise its distribution.
"It is apparent, of course, that the discoverer of a formula
for synthetic morphine could make far more money if he
should patent the process and manufacture the drug himself,
or sell it to a pharmaceutical manufacturer. He could make
many times $100,000 in that way. But my hope is that by the
assurance of a substantial reward I may stimulate the
efforts of scientists, who would take a scientific rather
than a sordid view of the problem.
"There are many chemists in this country who would gladly
turn over such a formula as a safeguard for the public
health to the Government if they were sure of recompense
from some other source for the labor, time and material
they had put into their experiments.
DIFFICULT BIT OF CHEMISTRY
"The molecule of morphine is extremely complicated, and is
not even yet known with certainty. A synthetic laboratory
compound duplicating it would, of course, have the same
physiological effect as morphine. It would be a narcotic,
and probably it would be habit-forming. It would be as
dangerous to health and morals, I suppose, as morphine is
now. We have synthetic substitutes for cocaine, not
precisely the same in atomic structure, which are not
habit-forming; but my offer is for a synthetic drug exactly
duplicating morphine, not a similar substance that will
serve as a substitute. Only thus can we eradicate
poppy-growing.
"To say that anybody who had the formula could make
synthetic morphine is preposterous. The process would
require an elaborate equipment, and if the thing were to be
done on a scale to make it cheap and profitable, there should
be a large laboratory, with huge stocks of materials. It
could not be done in a back room or a cellar.
"There would be a period, I think, during which some persons
would attempt to evade the law, just as they are now evading
the law against the manufacture and sale of alcoholic
liquor. There is, as a fact, an immense organized industry
in the smuggling of opium and opium products, such as
morphine and heroin. But if the issue were removed from
international politics, so that the great countries of the
world, including Great Britain, would cooperate in enforcing
regulations against this international traffic, I am
confident that in time it would die out, just as I am
confident that as time goes on we shall see a stricter
observance of the prohibitory laws against alcohol in this
country.
EXTENT OF DRUG ADDICTION
"My motive in offering the reward is to stimulate research,
in the hope of finding a synthetic equivalent of morphine,
which is now the main item in the cargoes of international
smugglers. Once we put the production of morphine on a
commercial manufacturing basis, instead of an agricultural
basis as at present, the Government of the world will be
much better able to cope with the evil of drug addiction.
"Nine-tenths of the dope fiends in this country, I am told,
are criminals; and the estimates of the United States Health
Service are that between 100,000 and 150,000 persons are
drug addicts. If the manufacture of morphine is limited
under Government licenses, the business will be fully
controlled in time. The next generation will not fight it;
the generation after that will forget it."
China, for years the chief smoker of opium, is today the
world's greatest user of morphine, and whatever morphine is
used there for other than medical purposes is smuggled into
the country. Opium - and in consequence morphine - is an
item of international politics and a danger spot in foreign
relations, because China no longer produces the drug, while
India is the great centre of the poppy-growing industry.
The phrase "British opium monopoly" is not mine. It recurs
constantly in official British documents. The Blue Books
issued by the British Government discuss it frankly and the
Colonial Office has an Opium Administration.
This situation which makes it difficult to deal with the
international smuggling of opium. The first International
Opium Conference under the auspices of the League of Nations
was convened last November at Geneva. All the countries
that still permit the smoking of opium were represented,
and in the later sessions the United States was represented
by a large delegation, which was hopeful that means might
be devised of terminating its use. It failed to accomplish
anything, because the British delegates blocked all efforts
in that direction.
THE OPIUM MONOPOLY
Let us examine now one of the British Blue Books:
"The opium revenue," it says, "is partly raised by a monopoly
of the production of the drug in Bengal and the United
Provinces, and partly by the levy of a duty on all opium
imported from native states. The crop is grown under the
control of a Government department, which arranges the total
area which is to be placed under the crop with a view to the
amount of opium required.
"The cultivator of opium in these monopoly districts receives
a license, and is granted advances to enable him toprepare
land for the crop, and he is required to deliver the whole of
the product at a fixed price to opium agents, by whom it is
dispatched to the Government factories at Patna and Ghazipur.
"The money advanced to the cultivator bears no interest.
The British Indian Government lends money with out interest
in no other cases. Producers of crops other than opium are
obliged to get along without free money."
When the opium has been manufactured - I am still taking my
facts from official British sources - that part which is for
consumption within India is turned over to Excise
Department; and the "provision opium," which is to be
exported to China, is sold at auction in Calcutta to the
highest bidders among a crowd of Parsees, Mohammedans,
Hindus and Asiatic Jews. It thus passes out of the hands of
the British Government. The revenue to the government, from
licenses, duties and auctions sales, has run as high as
$22,000,000 a year.
TONS OF DRUG SMUGGLED
From the Statesman's Year Book we learn that the exports of
opium from India to China were, until 1907, in Government
hands. Then an arrangement was made to stop the exports
when China should suppress the production of opium within
her own borders. By 1916 there was no longer legalized
governmental export of the drug between the two countries.
It has been charged that persons in both Japan and the
United States have assisted in the smuggling of morphine
into China since it was made illegal. The traffic is now
forbidden by international treaties, but tons of morphine,
nevertheless, has gone from New York and from England to
Japan and other Far Eastern points, and has been
transshipped for smuggling into China. All these facts have
been known for a long while, and are repeated here only as
bearing on the proposal Mr. Metz has made that the problem
shall be met on the economic basis by making the agricultural
production of the drug unprofitable.
There are those who say that opium smoking in moderation is
not more harmful than tobacco smoking; there are even those
who say that the use of morphine in moderation does no great
harm to Orientals. In China, as a fact, the poppy has been
known for twelve centuries and has been used medically for
nine centuries. But is was not until the seventeenth century
that the Dutch taught the Chinese how to smoke opium, and not
until the eighteenth century that an imperial edict was
issued against it.
THE OPIUM WAR
In 1839 a Chinese official seized 200 chests of the drug
from British vessels and destroyed them; whereupon the
British bombarded and took Canton, seized Chinese revenue
ships on the Yangtse Kiang, and made war along the coast.
When peace concluded "the Opium War." China surrendered
to England the island of Hongkong, paid an indemnity of
$21,000,000, and agreed to open up five treaty ports for
trade, not only in opium but in other commodities also.
Thereafter whole Chinese provinces diverted their rich river
bottoms to the cultivation of the poppy, and China "rolled
her own." After the agreement of 1907, however, the
cultivation of the drug was made illegal, and was finally, in
the course of ten years, stamped out completely. Travelers
sometimes report that in Szechuan, a vast inner province of
the country, small poppy fields have been seen; but
certainly the plant is not cultivated to any appreciable
extent. Whatever opium and whatever derivative drugs are
sold nowa-days in China come originally from other lands.
If morphine could be made in the laboratory more cheaply
than from poppies, it might still be smuggled into China.
Probably for a time it would be so smuggled. What Mr. Metz
hopes to see is the removal of stumbling blocks to
international regulation. He believes that when morphine is
manufactured rather than grown the nations of the world will
cooperate successfully to prevent illicit traffic in it.



Edgar Cayce Readings © 1971, 1993, 1994, 1995 by the Edgar Cayce Foundation